Euphillin (Syrup)
Bronchodilator and Spasmolytic
COMPOSITION:
Each 5ml Syrup contains 57mg Diprophylline.
INDICATIONS:
Diprophylline is theophylline derivative and has its effects.
It is better tolerated by mouth. Euphillin relaxes smooth muscle and relieves bronchospasm. Euphillin syrup is indicated mainly due to its dilating and bronchospasmolytic effects in the following:
- Allergic asthma, pulmonary edema and pneumonitis.
- Acute infection of respiratory tract.
- The pulmonary disorders due to cardiac dysfunction.
- Chronic cases of asthma as a preventive measurement to avoid or prevent asthmatic seizures during day and night.
DOSAGE:
Infants: 5 mg / kg weight, 3 times daily.
Children: 1 tablespoon, 3 times daily.
Adults: 2 tablespoons, 3 times daily.
Or otherwise as instructed by physician.
SIDE EFFECTS:
Central nervous system stimulation, palpitation, restlessness, vertigo, insomnia, headache and nausea, may occur.
CONTRAINDICATIONS:
It should be given with caution to patients with hyperthyroidism, hypertension, cardiac arrhythmias, hepatic dysfunction, fever and renal failure. Concomitant use with other xanthine medications should be avoided.
DRUGINTERACTIONS:
Propranolol, cimetidine, atropine, erythromycin and some other macrolides antibiotics may result in decreased clearance and increased serum half-life. Phenytoin and some other anticonvulsants as well as smoking may increase diprophylline clearance necessitating an increase in dose or dose frequency.
ABSORPTION:
Euphillin is rapidly absorbed from gastric mucosa and is largely excreted unchanged in the urine with an elimination half-life of approximately two hours.
PRESENTATION:
Carton pack contains glass bottle of 100ml, with leaflet.
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