What is Allergy-Crom?
It is a new anti-allergy eye drop from Domina Pharmaceuticals
Active ingredient: Cromolyn sodium
Available in 10ml (each 1ml contains 2mg of Cromolyn sodium)
What is Allergy-Crom used for?
It is FDA approved for the symptomatic treatment allergic eye disorders like
vernal conjunctivitis, keratoconjunctivitis, and keratitis.
What is Allergy-Crom’s mechanism of action?
Cromolyn sodium is a mast cell stabilizer, meaning it inhibits the mast cell degranulation and stops the release
of inflammatory mediators like histamine and leukotrienes that are responsible for allergic symptoms.
How is Allergy-Crom different from other anti-allergy eye drops?
Other anti-allergy eye drops have both antihistamine and mast cell-stabilizing properties.
However, cromolyn sodium only has mast cell-stabilizing properties, thus it is useful in persistent or recurrent allergic conjunctivitis
. It could also be used for patients who suffer from seasonal allergic conjunctivitis, who do not tolerate other therapies and can
estimate when their symptoms will begin. Treatment usually starts 2-4 weeks before the pollen season.
How is Allergy-Crom used?
1-2 drops in each eye 4-6 times daily. Symptomatic relief is frequently noticeable after a few days; maintain
therapy for as long as necessary.
Can Allergy-Crom be used in children?
Yes, it can be used on children 4 years and above
What are some facts about Allergy-Crom?
- Cromolyn sodium eye drops should be used consistently for 2 weeks for them to be effective.
- Cromolyn sodium eye drops should not be used for more than 4 weeks after the bottle is opened.
- Can be kept in the refrigerator; when used as an eye drop, the cooling sense can help with symptoms
What are the benefits of Allergy-Crom?
- Used for recurrent or persistent allergic conjunctivitis
- Most prescription medications can be taken safely with sodium cromoglicate eye drops.
- Can be used in children 4 years and above
- Can be used during pregnancy
- Has very low side effects
References:
1.Minutello K. Cromolyn Sodium 2023 [Available from: https://www.ncbi.nlm.nih.gov/books/NBK557473/.
2.Ophthalmology AAo. Conjunctivitis 2023 [Available from: https://www.aao.org/education/preferred-practice-pattern/conjunctivitis-ppp-2018.
3.Hamrah P. allergic conjunctivitis treatment 2023 [Available from: https://www.uptodate.com/contents/allergic-conjunctivitis-management?search=allergic%20conjunctivitis%20treatment&source=search_result&selectedTitle=2~150&usage_type=default&display_rank=2#H12817219.
4.Lexicomp. Cromolyn sodium (Ophthalmic) (Lexi-Drugs Multinational). 2023; Available from: https://online-lexi-com.ezproxy.lau.edu.lb:2443/lco/action/doc/retrieve/docid/multinat_f/4668192?cesid=7OT3G0M3Gy5&searchUrl=%2Flco%2Faction%2Fsearch%3Fq%3Dcromolyn%2Bsodium%26t%3Dname%26acs%3Dtrue%26acq%3Dcromolyn#adr